Fig. 3.

Group interaction results. a Left DLPFC HC > PD (masked with main effect HC): increased coupling between the left DLPFC and the right insular cortex in healthy controls compared with PD patients. On the right is depicted the estimate of the right insular cortex peak voxel comparing healthy controls with PD patients. b Left DLPFC PD < HC (masked with negative coupling PD): more negative coupling between the left DLPFC and the SFG in PD patients compared with healthy controls. On the right is shown the estimate of the SFG peak voxel comparing healthy controls with PD patients. c Left superior frontal gyrus PD > HC (masked with main effect PD): increased coupling between the left SFG and the bilateral perirhinal cortex in PD patients compared to healthy controls. The connectivity difference with the left perirhinal cortex spreads into a larger region encompassing mostly white matter in the left temporal cortex. On the right the estimate of the right perirhinal cortex peak voxel comparing healthy controls with PD patients is shown. d Right superior frontal gyrus HC > PD (masked with main effect HC): Greater negative coupling between the right SFG and dorsal ACC in PD patients compared with healthy controls. On the right the estimate of the dorsal ACC peak voxel comparing healthy controls with PD patients is shown. e Right superior frontal gyrus PD < HC (masked with negative coupling PD): more negative coupling between the right SFG and the dorsal ACC, primary motor cortex, parietal cortex and precuneus in PD patients compared with healthy controls. On the right the estimate of the primary motor cortex peak voxel comparing healthy controls with PD patients is shown