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. 2016 Mar 31;184(3):338–346. doi: 10.1111/cei.12767

Figure 2.

Figure 2

Terminal complement complex (TCC) levels are increased in serum of multibacillary leprosy patients with reaction compared to patients from Ethiopia without reaction. Meso Scale discovery (MSD) assay for measuring the common complement pathway activation fragment iC3b (a) and the terminal pathway activation marker TCC (b), in serum samples of pauci‐bacillary (n = 7) and multi‐bacillary patients without a reaction (n = 23) or with a reaction (n = 15). Although no significant difference was found in the levels of iC3b in serum of pauci‐bacillary and multi‐bacillary patients without and with a reaction, TCC levels were increased significantly in multi‐bacillary leprosy patients with a reaction comparted to pauci‐bacillary and multi‐bacillary patients without a reaction [mean TCC no reaction 4·03 mg/l [standard error (s.e.) = 0·28) versus mean TCC reaction 7·49 mg/l (s.e. = 1·48); P < 0·01 and P < 0·05]. The error bars represent the standard error of the mean (s.e.).