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. Author manuscript; available in PMC: 2016 May 19.
Published in final edited form as: Am J Chin Med. 2015 Sep 22;43(6):1211–1230. doi: 10.1142/S0192415X1550069X

Figure 2.

Figure 2

Effect of general CYP inhibitor 1-aminobenzotriazole (ABT) on in vitro human liver microsomal (HLM) metabolism of D and DA. Panel a. D with solvent vehicle. Panel b. D with ABT. Panel c. DA with solvent vehicle. Panel d. DA with ABT. HLM was first incubated with ABT (b & d) or vehicle (a & c) for 20 minutes before D or DA was added to the reactions. Reactions were terminated after 60 minutes. UV detection wavelength was 330nm for HPLC-chromatograms. M6 and N8 correspond to respective mono-oxygenated metabolite of D and DA in HLM incubation we previously identified (Li et al., 2013a).