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Effects of oral administration of general CYP inhibitor 1-aminobenzotriazole (ABT) on plasma concentration and prostate content of D, DA and DOH in mice. Panel a, D; Panel b DA; Panel c, DOH. Control mice received water and ABT group received 3 mg ABT gavage per mouse 2 h prior to D/DA dose. Mice were given gastric gavage of 6 mg D/DA mixture (3.6mg D and 2.4 mg DA). Blood and prostate samples were collected 1 or 2 hours after administration of D/DA mixture.
