Table 2.
Allele frequencies of CYP SNP polymorphisms: comparison between literature reports and data from our study subjects.
| CYP allele designation | Mutation | refrence SNP ID | Allele frequency (%)
|
|||||
|---|---|---|---|---|---|---|---|---|
| Literature | A12-3742 | |||||||
|
| ||||||||
| Caucasian | Hispanic | Asian | Caucasian (n=13) | Hispanic (n=4) | Asian (n=3) | |||
| CYP2C9*2 | 3608C>T | rs1799853 | 10~17 | 6.5 | 0~2 | 12 | 0 | 0 |
| CYP2C9*3 | 42614A>C | rs1057910 | 6 | N.A. | 2~6 | 8 | 12 | 0 |
| CYP2C19*2 | 19154G>A | rs4244285 | 6~15 | 15 | 22~32 | 12 | 0 | 33 |
| CYP2C19*3 | 17948G>A | rs4986893 | 0~1 | 0~1 | 3~7 | 0 | 0 | 0 |
| CYP2C19*17 | −806C>T | rs12248560 | 21~25 | N.A. | 0~2 | 35 | 0 | 17 |
| CYP2D6*4 | 1846G>A | rs3892097 | 15~25 | 1~10 | 1~10 | 19 | 0 | 0 |
| CYP3A4*22 | 15389C>T | rs35599367 | 2.5~8 | N.A. | 4.3 | 15 | 0 | 0 |
| CYP3A5*3 | 6986A>G | rs776746 | 88~97 | 66~75 | 66~75 | 100 | 75 | 100 |