Table 1. Participant characteristics.
Expressed emotion selection |
Peer affiliation selection |
|||||
---|---|---|---|---|---|---|
N | M | s.d. | N | M | s.d. | |
Number of families | 150 | 261 | ||||
ADHD diagnosis | 153 | 79% | 166 | 39% | ||
Inattentive subtype | 68 | 35% | 74 | 17% | ||
Hyperactive–impulsive subtype | 18 | 9% | 25 | 6% | ||
Combined subtype | 67 | 35% | 67 | 16% | ||
Subthreshold ADHD | 19 | 10% | 43 | 10% | ||
Unaffected | 21 | 11% | 220 | 51% | ||
ADHD severity (CPRS) | 191 | 20.94 | 12.18 | 418 | 12.08 | 12.25 |
ODD diagnosis | 46 | 24% | 50 | 12% | ||
CD diagnosis | 11 | 6% | 11 | 6% | ||
History of stimulant use | 136 | 70% | 145 | 34% | ||
Male | 127 | 66% | 237 | 55% | ||
Collection site (Amsterdam) | 80 | 42% | 216 | 50% | ||
Age | 193 | 17.15 | 3.24 | 429 | 17.48 | 3.52 |
Estimated IQ | 193 | 97.54 | 14.85 | 426 | 101.62 | 12.25 |
Maternal warmth/positive peer affiliation | 193 | 1.64 | 0.89 | 429 | 22.52 | 3.58 |
Maternal criticism/deviant peer affiliation | 193 | 1.65 | 0.92 | 429 | 15.01 | 4.44 |
MRT reward condition (ms) | 193 | 298.81 | 39.44 | 429 | 298.25 | 36.73 |
MRT non-reward condition (ms) | 193 | 332.05 | 50.01 | 429 | 329.48 | 47.62 |
Variability reward condition (ms) | 193 | 0.21 | 0.14 | 429 | 0.19 | 0.11 |
Variability non-reward condition (ms) | 193 | 0.25 | 0.15 | 429 | 0.24 | 0.15 |
Bold response reward anticipation | ||||||
VS | 167 | 196.90 | 841.49 | 375 | 267.14 | 828.11 |
vmPFC | 167 | −508.21 | 1882.21 | 375 | −412.53 | 2132.62 |
Bold response reward receipt | ||||||
VS | 167 | 604.36 | 1542.24 | 375 | 408.06 | 1540.83 |
vmPFC | 167 | 1722.58 | 3714.42 | 375 | 1498.62 | 4225.33 |
DAT1 | 186 | 407 | ||||
9-repeat present | 62a | 33% | 150b | 37% | ||
9-repeat absentc | 124 | 67% | 257 | 63% | ||
5-HTT | 190 | 416 | ||||
Short allele present | 123d | 65% | 269e | 65% | ||
Short allele absent | 67 | 35% | 147 | 35% | ||
DRD4 | 190 | 417 | ||||
7-repeat present | 64 | 34% | 143 | 34% | ||
7-repeat absent | 126 | 66% | 274 | 66% |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; CD, conduct disorder; CPRS, Conners Parent Raring Scale; IQ, intelligence quotient; MRT, mean reaction time; ODD, oppositional defiance disorder; vmPFC, ventral medial prefrontal cortex; VS, ventral striatum.
ODD and CD diagnoses were based on Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS) structured psychiatric interviews.47
Estimated IQ was based on two subtests of the Wechsler Intelligence Scale for Children (WISC)/ Wechsler Adult Intelligence Scale (WAIS-III): Vocabulary and Block Design.48, 49
N=12 (7%) with two 9-repeats.
N=20 (5%) with two 9-repeats.
10/10 genotype.
N=28 (15%) with two short alleles.
N=59 (14%) with two short alleles.