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. 2016 Apr 12;6(4):e777. doi: 10.1038/tp.2016.40

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Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Scatter plot of total distribution volume values (V_T) in the cortical and subcortical regions in patients with recent onset of schizophrenia (SZ) and healthy controls (HC) injected with [¹¹C]DPA-713. Individual patient and healthy control V_T data are shown along with mean values and standard deviation. Using two-way analysis of variance with genetic group (C/C vs C/T) and cohort (SZ vs HC) as independent, fixed factors, regional V_T values in each of the six cortical regions (insula (In), cingulate (CCx), parietal (PC), frontal (FC), temporal (TC) and occipital (OC)) and two subcortical regions (hippocampus (Hp), amygdala (Am)) did not significantly differ. The threshold for significance after accounting for multiple comparisons was P<0.06/8=0.006.