Figure 1.
MAOA methylation change (% of T0; T1–T0) in responders and non-responders to CBT. Change in MAOA methylation (%) from baseline (T0) to post cognitive behavioral therapy (CBT; T1) in the discovery sample stratified for responders (N=11; black bars, mean) and non-responders (N=17; white bars, mean) for average methylation, as well as at single CpG sites (error bars: ±s.e.). For definition of responders/non-responders see section ‘Treatment' under ‘Patients and Methods'. *Significant at P<0.05; **significant at P⩽0.01; ***significant at P⩽0.001.