Table 3. APOE genotype of all cases (excluded confirmed pathogenic variants) and controls.
Study size |
APOE genotype |
|||||||
---|---|---|---|---|---|---|---|---|
4/4 | 3/3 | 2/2 | 4/3 | 3/2 | 4/2 | ɛ4 carrier | ||
Controls | 93 | 1 | 54 | 2 | 24 | 12 | 0 | 25 |
DLB patients | 87 | 3 | 33 | 0 | 45 | 6 | 0 | 49 |
P-value | 0.35 | 0.0076 | 0.50 | 0.0004 | 0.22 | 1.0 | 0.0001 |
Abbreviation: DLB, dementia with Lewy body.
Comparison between groups (patients n=87, controls n=91) performed by Fisher's exact test. APOE ɛ4 carrier determined by the presence of at least one APOE ɛ4 allele.