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. 2016 Feb 9;6(2):e733. doi: 10.1038/tp.2016.1

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Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Changes in DA system after restraint stress and MPTP treatment. (a) Level of DA and its metabolite DOPAC in striatal homogenates of the four groups of C57BL/6 mice receiving vehicle (CTR, n=10); MPTP (n=12); MPTP+RI (n=9); and RI (n=9) (*P<0.05). (b) Representative western blot analysis of striatal levels of DA receptors D1DR and D2DR in the same groups of mice and densitometric analyses of their immunoreactivities (*P<0.05). Results are mean ±s.e.m. DA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; RI, restraint/isolation. **P<0.001.