Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 16;6(2):e736. doi: 10.1038/tp.2016.7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Deletion of Nlgn2 attenuates the overall inhibitory inputs to PrL, especially the synaptic inhibition from IL to PrL. (a–c) Sample traces (a), averaged amplitude (b) and averaged frequency (c) of spontaneous IPSCs in pyramidal neurons of PrL; (d–f) Sample traces (d), cumulative probability of amplitude (e) and frequency (f) of miniature IPSCs in pyramidal neurons of PrL; (g and h) Sample traces (g) and average amplitudes (h) of IPSCs in layer II/III pyramidal neurons of PrL evoked by stimulation in IL in wild-type (WT) and Nlgn2^−/− mice. Note that the numbers within the bar diagrams n/N indicate the number of cells (n) tested/number of mice (N). IL, infralimbic cortex; IPSC, inhibitory postsynaptic current; PrL, prelimbic cortex.