Table 6. Logistic regression modeling of rs6295 and childhood trauma.

Childhood trauma	Psychiatric hospitalization		Suicide attempt		Past substance abuse		Depression		PTSD
	OR	P	OR	P	OR	P	OR	P	OR	P
Discovery sample
rs6295GG	1.586	0.026	1.531	0.049	1.515	0.021	1.179	0.338	1.265	0.175
Male sex	0.722	0.123	0.34	<0.001	2.091	<0.001	0.855	0.364	1.073	0.684
Age	1.219	0.001	1.2	0.002	1.428	<0.001	1.093	0.044	1.065	0.157
Age2	0.998	0.003	0.998	0.007	0.996	<0.001	0.999	0.053	0.999	0.168
Disability	2.32	<0.001	2.186	0.001	1.127	0.565	0.999	0.998	1.207	0.378
Moderate traumaa	1.569	0.073	1.870	0.019	1.568	0.036	2.585	<0.001	2.589	<0.001
Severe traumaa	2.432	<0.001	4.900	<0.001	2.865	<0.001	3.596	<0.001	5.086	<0.001
Test sample
rs6295GG	2.526	0.003	1.507	0.184	1.241	0.419
Male sex	1.196	0.585	0.752	0.378	1.999	0.008
Age	1.281	0.005	1.243	0.009	1.416	<0.001
Age2	0.997	0.006	0.997	0.010	0.996	<0.001
Disability	3.185	0.001	1.893	0.074	1.507	0.167
Moderate traumaa	2.019	0.071	1.879	0.086	1.126	0.698
Severe traumaa	7.338	<0.001	5.586	<0.001	3.446	<0.001

Abbreviation: PTSD, posttraumatic stress disorder.

^aRelative to mild trauma.

Odds ratios (OR) and P-values (P) for P<0.05 are shown in bold.