Table 2. Effects of (−)-OSU6162 on aggressive behavior in female rats.
| n | Aggression composite (±s.e.m.) | P-value vs saline | Social behavior (s) (±s.e.m.) | P-value vs saline | |
|---|---|---|---|---|---|
| Saline | 12 | 30.0 (±5.8) | — | 151.5 (±16.5) | — |
| OSU 75 | 12 | 5.8 (±2.5) | 0.0001 | 142.6 (±13.3) | NS |
| OSU 200 | 13 | 5.9 (±2.8) | 0.0001 | 120.0 (±17.5) | NS |
Abbreviation: NS, not significant.
Aggressive and social behavior during the resident intruder test in female rats studied in the diestrus phase and pretreated with saline, (−)-OSU6162 (75 μmol kg−1; OSU 75), or (−)-OSU6162 (200 μmol kg−1; OSU 200). Data are presented as mean (±s.e.m.).