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. 2016 Mar 29;6(3):e765. doi: 10.1038/tp.2016.32

Table 2. Difference in DNA methylation levels between neonates born to anxious versus non-anxious mothers, stratified by birth weight.

CpG unit Lower birth weight (3530 g)
Higher birth weight (>3530 g)
  Δ 95% CI P Δ 95% CI P
IGF2 DMR0
 3 −1.66% −3.91 to 0.59% 0.15 −1.96% −4.10 to 0.18% 0.072
 4 0.30% −2.23 to 2.84% 0.81 0.40% −2.89 to 3.70% 0.81
 6.7 −0.88% −2.78 to 1.01% 0.36 0.79% −0.86 to 2.14% 0.34
 Average −1.00% −2.71 to 0.70% 0.25 −0.09% −2.04 to 1.85% 0.92
             
IGF2/H19 ICR
 1 −4.33% −6.83 to −1.84% 0.0007 −0.70% −2.83 to 1.44% 0.52
 5.6.7.8 −3.40% −5.71 to −1.10% 0.0040 −0.45% −2.63 to 1.73% 0.68
 11.12 −3.82% −6.10 to −1.55% 0.0011 −0.47% −2.53 to 1.63% 0.66
 13.14 −4.57% −6.99 to −2.14% 0.0003 −0.25% −2.31 to 1.80% 0.81
 21.22 −3.76% −6.49 to −1.04% 0.0071 0.27% −2.35 to 2.88% 0.84
 23 −2.21% −5.19 to 0.78% 0.15 −1.49% −4.47 to 1.49% 0.33
 Average −3.89% −6.06 to −1.72% 0.0005 −0.59% −2.54 to 1.37% 0.55

Abbreviations: DMR, differentially methylated region; ICR, imprinting control region.