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. Author manuscript; available in PMC: 2016 May 19.
Published in final edited form as: BMJ Qual Saf. 2011 Sep 2;21(1):54–62. doi: 10.1136/bmjqs-2011-000041

Table 4.

Change Strategies For Evaluation and Further Consideration

NPO with clear fluids allowed up to 2–4 hours prior to PCI
N-acetylcysteine 1200mg PO q12° x 4, first dose 6pm night before PCI: 1200mg dose @ 6PM, 6AM, 6PM, 6AM
 Standardization of volume administration prophylaxis
  IV NS @ 1.5mL/kg/hr at 10pm night before PCI, continue until IV NaHCO3 protocol begins
  IV NaHCO3 @ 3mL/kg/hr for 1 hour pre-PCI (reduce to 1mL/kg/hr if PCI is delayed)
  IV NaHCO3 @ 1mL/kg/hr for 6 hours post-PCI
Recommendation: Post-discharge follow-up at 3–5 days to determine CI-AKI, if persistent weekly labs until resolved
Iopamidol low-osmolar contrast agent

CI-AKI = contrast-induced acute kidney injury; PCI = percutaneous coronary intervention; IV=intravenous; NS = normal saline; NaHCO3 = sodium bicarbonate (1000mL D5W mixed with 150 mEq NaHCO3).