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. 2016 May 19;6:26277. doi: 10.1038/srep26277

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Scratched monolayer cells were treated with 1 mM bupivacaine for 24 h. Degree of wound healing was calculated as (initial wound area − remaining wound area)/initial wound area. (A) Bupivacaine suppressed wound closure in SKOV-3 cells. (B) Bupivacaine suppressed wound closure in PC-3 cells. All values are presented as mean ± SD (n = 4); ***P < 0.001.