Table 1.
Clinical profile: gender, age, seizures characteristics, antiepileptic therapy, and electro-clinical diagnosis from the multi-disciplinary team (MDT) established on the basis of clinical information and electrophysiological findings.
| Pt n° | Sex | Age | Years since beginning | Type of seizures | Seizures frequency | Relevant history | Current antiepileptic therapy | MDT |
|---|---|---|---|---|---|---|---|---|
| 1 | F | 30 | 20 | Complex partial | 12/month | Negative | CBZ, LEV | Right temporal |
| 2 | F | 28 | 25 | Complex partial | 4–6/day | Negative | LTG, PG, PRP | Right temporo-parietal |
| 3 | F | 40 | 20 | Simple partial with SG | 7/month; 1/year (SG) | Febrile convulsion | CBZ, PG | Right temporal |
| 4 | F | 44 | 30 | Complex partial SG | 3–20/month; 1/year (SG) | Meningitis | LEV | Right temporal |
| 5 | M | 23 | 3 | Simple partial | 1–2/week | Febrile convulsion | ESL | Right parietal |
| 6 | M | 39 | 14 | Simple partial with SG | 1–2/week; rare (SG) | Negative | LTG, LEV, RTG | Left fronto-temporal |
| 7 | F | 39 | 18 | Simple partial with SG | 1–5/daily; rare (SG) | Negative | OCX, CLZ, PHE | Left fronto-temporal |
| 8 | M | 22 | 6 | Complex partial with SG | 6–8/month; 1–3/month (SG) | Negative | ZNS, LEV, CLZ | Left temporo-parietal |
| 9 | M | 19 | 15 | Simple partial with SG | 1–2/week; 1–2/month (SG) | Negative | CLZ, OCX, LEV | Right fronto-temporal |
| 10 | F | 33 | 17 | Complex partial | 1–2/week | Negative | LTG, ZNS | Left temporo-occipital |
| 11 | F | 19 | 5 | Complex partial with SG | 4–5/day; 2–3/week (SG) | Negative | LTG, LEV, ZNS, OCX | Left frontal |
| 12 | M | 23 | 14 | Complex partial | 1/day | Negative | VPA, ESL, TPM, LEV | Left frontal |
| 13 | M | 23 | 19 | Simple partial | 2–3/night | Negative | ZNS, LEV, CLZ | Right frontal |
| 14 | M | 65 | 16 | Complex partial | 1/day | Negative | VPA, LTG | Left temporal |
| 15 | F | 41 | 17 | Complex partial | 2–3/day | Negative | ZNS, ESL, CLZ | Right temporal |
| 16 | M | 31 | 15 | Simple partial with SG | 2/month; rare (SG) | Negative | LEV, LCM | Right temporal |
| 17 | M | 38 | 8 | Complex partial with SG | 1–2/month; rare (SG) | Negative | OCX. CLZ, ZNS, VPA | Left temporal |
| 18 | F | 55 | 49 | Complex partial | 2–3/week | Negative | VPA, CBZ, CLZ, ZNS | Right fronto-temporal |
| 19 | F | 39 | 30 | Complex partial | Several/week | Negative | OCX, TPM, CLP, CLZ | Left temporal |
| 20 | M | 40 | 7 | Complex partial | 3/week | Negative | CBZ, LTG | Right temporal |
SG = secondary generalization; CBZ = carbamazepine; LEV = levetiracetam; LTG = lamotrigine; PG = pregabilin; PRP = parampanel; ESL = eslicarbazepine; RTG = retigabine; OCX = oxocarbazepine;CLZ = clobazam; PHE = phenytoin; ZNS = zonisamide; VPA = valproate; TPM = topiramate; LCM = lacosamide; CLP = clonazepam.