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. 2015 Dec 29;7(6):6693–6710. doi: 10.18632/oncotarget.6793

Figure 1. ANXA1 is a crucial mediator of HIF-1α-independent cellular proliferation.

Figure 1

(A, B) Anchorage-dependent proliferation of HIF-1α-deficient (HIF-) and control (SCR) AGS and MKN28 cells under normoxia. Results shown are representative of three independent experiments and values represent the mean ± SEM of triplicate determinations. (C) Analysis of ANXA1 expression in AGS HIF- and SCR cells by immunoblot using whole cell lysates harvested at five different time points. YY-1 served as loading control. (D) Chromatin status of the ANXA1 promotor in AGS HIF- and SCR cells was determined by chromatin immunoprecipitation. Representative gels of four independent experiments are shown.