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. 2016 Jan 8;7(6):6902–6915. doi: 10.18632/oncotarget.6849

Figure 3. R152C mutation impairs BER efficiency in vitro.

Figure 3

A. SDS-PAGE of purified BER proteins. SP-BER B. or LP-BER C. reconstitution with purified BER proteins. The top part of each panel shows the schematic structures of the corresponding DNA substrates. The middle shows PAGE-separated products and the bottom the relative percentage of repaired product obtained with the indicated amounts of Pol β. Values represent the mean ±SD of three independent assays.