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. 2016 Jan 11;7(6):7149–7160. doi: 10.18632/oncotarget.6880

Figure 7. Scheme of proposed mechanism for regulation of c-Myc by miRNA on PRIMA-1Met treatment.

Figure 7

miRNA-29a-mediated targeting of c-Myc by PRIMA-1Met may occur as a direct inhibitory effect of the miRNAs. Alternatively, such inhibition can be seen as an indirect effect of the miRNAs which may be mediated by other targets including Mcl-1 or Bcl-2.