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. 2016 May 19;116(6):862–869. doi: 10.1093/bja/aew116

Table 2.

Data are presented as mean (sd). The first statistical change compared with 14 cm H2O PEEP is indicated by *P<0.05 was considered significant. Tidal volume (VT), Airway dead space (VDaw), Alveolar dead space (VDalv), Alveolar dead space to alveolar tidal volume ratio (VDalv/VTalv), Normalized slope of phase III (SnIII), Amount of expired CO2 within one breath (VTCO2,br), Volume of phase III to tidal volume ratio (VIII/VT), Arterial minus end-tidal partial pressure of CO2 (Pa-ETCO2), Arterial partial pressure of O2 (PaO2), Arterial partial pressure of CO2 (PaCO2), Fraction of inspired oxygen (FIO2)

Dead space variables, blood gas analysis and compliance during the decremental PEEP trial
PEEP (cm H2O) 14 12 10 8 6 4 2 0
VT (ml) 472 (80) 476 (77) 474 (80) 473 (77) 472 (76) 471 (78) 474 (81) 473 (81)
VDaw (ml) 214 (40) 209 (42) 204 (39) 196 (40)* 188 (39) 182 (36) 174 (32) 167 (26)
VDalv (ml) 52 (37) 52 (34) 47 (31) 45 (33) 42 (33)* 35 (32) 39 (31) 35 (29)
VDBohr/VT 0.48 (0.06) 0.47 (0.07) 0.45 (0.07)* 0.43 (0.07) 0.40 (0.07) 0.38 (0.07) 0.35 (0.07) 0.33 (0.07)
VDEnghoff/VT 0.57 (0.07) 0.55 (0.08) 0.53 (0.08)* 0.52 (0.08) 0.49 (0.08) 0.47 (0.09) 0.46 (0.08) 0.44 (0.08)
VDalv/VTalv 0.19 (0.11) 0.18 (0.1) 0.17 (0.09) 0.15 (0.09) 0.14 (0.1)* 0.12 (0.1) 0.13 (0.09) 0.11 (0.09)
SnIII (mm Hg ml−1) 0.95 (1.19) 0.73 (0.64) 0.62 (0.31) 0.62 (0.43) 0.58 (0.33) 0.48 (0.25)* 0.47 (0.26) 0.50 (0.21)
VTCO2,br (ml) 12.5 (3.3) 13.3 (3.7)* 13.9 (3.7) 14.3 (3.6) 14.7 (3.7) 15.2 (3.7) 15.7 (3.8) 16.0 (3.9)
VIII/VT 0.42 (0.14) 0.39 (0.13) 0.41 (0.14) 0.43 (0.13)* 0.46 (0.13) 0.46 (0.13) 0.48 (0.12) 0.51 (0.11)
Pa-ETCO2 (mm Hg) 3.6 (2.8) 3.4 (2.5) 3.7 (2.6) 3.2 (2.5) 2.9 (2.7) 2.7 (2.4) 3.1 (2.4) 2.8 (2.5)*
PaCO2 (mm Hg) 43 (5) 43 (5) 44 (5) 43 (5) 42 (5) 42 (5) 42 (5) 41 (5)*
PaO2 (mm Hg) 138 (35) 140 (32) 145 (25) 145 (24) 145 (23) 139 (21) 132 (24) 127 (23)*
PaO2/FIO2 (mm Hg) 346 (87) 349 (80) 359 (71) 371 (71) 372 (68) 357 (65) 338 (72) 324 (70)*
Dynamic compliance (ml cm H2O−1) 34 (6) 36 (8) 35 (6) 35 (7) 35 (7) 34 (7) 33 (7) 31 (7)*