TABLE 1.

Univariate and multivariate analyses for overall survival for VEGF-A cohort

Variable	Caucasian (n = 181)				Asian (n = 115)
	Univariate analysis			Multivariate analysis	Univariate analysis			Multivariate analysi
	HR	95 % CI	p value	p value	HR	95 % CI	p value	p value
Age	1.015	0.992–1.039	0.200		1.077	1.031–1.125	0.001	<0.001
Gender	0.952	0.556–1.631	0.859		0.473	0.173–1.291	0.144
Location	1.295	1.048–1.600	0.017	<0.001	1.145	0.694–1.890	0.596
Margin status	4.066	2.152–7.680	<0.001
Neoadjuvant treatment	1.468	1.106–1.948	0.008		2.821	1.407–5.655	0.003
Adjuvant treatment	0.993	0.626–1.577	0.978		0.954	0.359–2.533	0.925
Lauren classification	0.987	0.728–1.338	0.933		0.930	0.488–1.775	0.827
Tumor size	1.134	1.069–1.202	<0.001	<0.001	1.225	1.037–1.447	0.017	0.264
Vascular invasion	1.334	0.808–2.201	0.260		2.662	1.129–6.274	0.025	0.866
Neural invasion	1.350	0.819–2.228	0.239		1.989	0.822–4.810	0.127
Grade	2.437	1.344–4.417	0.003	0.010	0.647	0.273–1.537	0.324
T status	1.618	1.277–2.050	<0.001	0.151	1.973	1.314–2.962	0.001	0.051
N status	1.518	1.215–1.896	<0.001	<0.001	1.815	1.315–2.504	<0.001	<0.001
VEGF-A level (high vs low)	2.438	1.411–4.212	0.001	0.034	0.591	0.245–1.426	0.242

Bold values are statistically significant (p < 0.05)