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. 2016 May 19;11(5):e0155400. doi: 10.1371/journal.pone.0155400

Fig 8. γ-secretase activity in SH-SY5Y cells.

Fig 8

SH-SY5Y cells were transfected with siRNA against ABCG1, ABCG4, or scrambled siRNA (control), and allowed to differentiate for 3 days. Cells were incubated in DMEM containing 0.02% BSA, 5 μM TO901317, and 5 μM 9-cis retinoic acid for 16 h. The activity of endogenous γ-secretase was determined using a γ-secretase assay kit. Experiments were performed in triplicate and the activities relative to those observed in control cells are represented as means with the SD. ** P < 0.01 compared with control cells.