Table 4. Relative kcat values and correlation coefficients between these values of 15 IgGs from plasma and CSFs in the hydrolysis of MHO, DNA, and MBP*.
| Number of patient | Amylase activity of plasma IgGs; kcat, min−1 | Amylase activity of CSF IgGs; kcat, min−1 | DNase activity of plasma IgGs x 103; kcat, min−1 | DNase activity of CSF IgGs x 102; kcat, min−1 | MBP-hydrolyzing activity of plasma IgGs x 103; kcat, min−1 | MBP-hydrolyzing activity of CSF IgGs; kcat, min−1 |
|---|---|---|---|---|---|---|
| Parameter number | 1 | 2 | 3 | 4 | 5 | 6 |
| 1 | 1.84 | 15.4 | 2.7 | 8.0 | 1.7 | 0.33 |
| 2 | 0.58 | 6.3 | 0.79 | 10.9 | 0.51 | 0.044 |
| 3 | 0.73 | 7.8 | 0.54 | 11.8 | 2.0 | 0.18 |
| 4 | 1.44 | 12.9 | 1.7 | 8.2 | 5.2 | 0.17 |
| 5 | 0.20 | 4.5 | 1.6 | 8.5 | 0.44 | 0.008 |
| 6 | 0.25 | 18.7 | 1.7 | 8.2 | 14.0 | 0.1 |
| 7 | 0.23 | 21.2 | 2.0 | 8.2 | 5.9 | 0.26 |
| 8 | 0.51 | 6.1 | 2.7 | 2.0 | 5.6 | 0.53 |
| 9 | 0.61 | 43.2 | 2.6 | 1.8 | 6.8 | 0.6 |
| 10 | 0.45 | 17.9 | 1.2 | 3.2 | 6.1 | 0.3 |
| 11 | 0.61 | 42.9 | 3.2 | 18.0 | 14.0 | 0.51 |
| 12 | 0.58 | 34.8 | 1.8 | 14.0 | 10.0 | 0.72 |
| 13 | 1.0 | 48 | 0.59 | 2.6 | 0.44 | 0.06 |
| 14 | 1.16 | 29.8 | 1.8 | 9.5 | 16.0 | 0.6 |
| 15 | 0.93 | 30.0 | 1.6 | 8.3 | 7.0 | 0.81 |
| Average values | 0.74±0.36 | 22.6±12.4 | 1.77±0.59 | 8.2±3.1 | 0.0064±0.0042 | 0.35±0.22 |
| Correlation coefficient | 1/2: 0.22; 1/3: 0.03; 1/4: −0.009; 1/5: −0.13; 1/6: 0.1; 2/3: 0.22; 2/4: 0.03; 2/5: 0.41; 2/6: 0.45; 3/4: 0.11; 3/5: 0.44; 3/6: 0.61; 4/5: 0.34; 4/6: 0.11; 5/6: 0.59 | |||||
*For each value, a mean of three measurements is reported; the error of the determination of each value does not exceed 7–10%.