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Topology-overlap matrix (TOM)-based connectivity network in the TLR, TCR, and BCR signaling pathways. Top 3% of gene pairs with largest TOM-based measures were selected to generate these networks. Red (yellow) dot: gene with significant increase (decrease) in expression in cases; circle: gene that is not differentially expressed between cases and controls. A: atherosclerosis; B: Ischemic Stroke; C: Myocardial Infarction.
