Table 3. Risk factors for selected cancer in transplanted recipients.
Head and neck | Liver | Bladder | Kidney1 | NHL | ALL | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | p-value | HR | p-value | HR | p-value | HR | p-value | HR | p-value | HR | p-value | |
Age at transplant (years) | 1.03 | 0.07 | 1.05 | <0.001 | 1.06 | <0.001 | 1.04 | <0.001 | 0.97 | <0.01 | 1.04 | <0.001 |
Sex | ||||||||||||
Male | 1 | (ref) | 1 | (ref) | 1 | (ref) | 1 | (ref) | 1 | (ref) | 1 | (ref) |
Female | 0.18 | 0.02 | 0.53 | 0.03 | 2.29 | <0.01 | 3.52 | <0.001 | 0.70 | 0.40 | 1.01 | 0.95 |
Calendar year of transplantation | 1.24 | 0.06 | 0.90 | 0.03 | 0.94 | 0.23 | 0.87 | 0.02 | 0.86 | 0.04 | 0.95 | 0.03 |
Transplanted organ | ||||||||||||
Heart | 1 | (ref) | 1 | (ref) | 1 | (ref) | 1 | (ref) | 1 | (ref) | ||
Kidney | 0.25 | 0.07 | 2.38 | 0.16 | 11.90 | 0.01 | 0.23 | <0.01 | 1.31 | 0.15 | ||
Liver | 2.13 | 0.18 | 7.05 | <0.01 | 1.08 | 0.95 | 0.55 | 0.23 | 1.52 | 0.04 |
HR = hazard ratio.
1The kidney cancers were all contributed from kidney transplantations and the model was adjusted for age at transplant (years), sex and calendar year of transplantation.