Fig 10. Prediction: Different schedules of antibiotic treatment.

Treatment with different schedules of Ampicillin or Moxifloxacin after infection with 5 ⋅ 10⁶ Streptococcus pneumoniae are simulated. Time series of pneumococcal population, neutrophils, IL-6, debris, EU, EA and macrophages in BALF are presented. Ampicillin 0.02 mg/g is given every 12 hours starting 24 hours after infection (dashed blue line) or every 48 hours starting 24 hours after infection (red line). Moxifloxacin 0.1 mg/g is given every 12 hours starting 24 hours after infection (dashed black line) or every 48 hours starting 24 hours after infection (green line).