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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Cancer Res. 2016 Mar 10;76(8):2076–2081. doi: 10.1158/0008-5472.CAN-15-1456

Figure 1. Cytosolic DNA sensing to activate STING promotes LLC growth in dermis and lungs.

Figure 1

A. LLC cells were injected intradermally into B6 (WT), STING-KO or IDO1-KO mice and tumor growth was monitored. BC. LLC cells were injected intravenously and CT scans were performed to assess tumor growth in lungs after 10 days (B) and lung weights after 12 days (C). Statistical significance was determined by two-way ANOVA with Bonferroni post hoc test (A) and two tailed unpaired Student’s t test (B,C); *p<0.05, **p<0.01, ***p<0.001, except IDO1-KO vs. WT in panel A, ###p<0.001.