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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Neuropharmacology. 2016 Feb 18;105:471–477. doi: 10.1016/j.neuropharm.2016.02.022

Figure 5. A calpain-2 selective inhibitor prolonged ERK activation in dorsal hippocampus.

Figure 5

A. Experimental design: Calpain-2 inhibitor (0.3 mg/kg) or Vehicle were injected (i.p.) in WT mice 30 min before training; dorsal and ventral hippocampi were collected 5 min and 50 min after training. B. Representative western blots for SCOP, Akt, p-ERK and ERK under various experimental conditions. C&D. Quantitative analysis of the levels of SCOP (normalized to Akt values) and p-ERK/ERK ratios. * p < 0.05 **p<0.01.