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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Neuropharmacology. 2015 Dec 31;105:61–71. doi: 10.1016/j.neuropharm.2015.12.025

Figure 8. No effects of subchronic oxytocin, or chronic clozapine or risperidone, on impaired sensorimotor gating in Grin1neo/neo mice.

Figure 8

A and B) Grin1 wild-type (+/+) and knockdown (neo/neo) mice were tested for prepulse inhibition of acoustic startle responses 48 hr after the final treatment in the subchronic regimen. C and D) Grin1 mice were tested on day 15-16 of the chronic clozapine regimen (66 mg/kg/day). Data were omitted from one male Grin1neo/neo mouse in the clozapine-treated group with extremely low startle amplitudes. E and F) Grin1 mice were tested 3-6 days following the chronic risperidone (21 day; 2.0 mg/kg/day) regimen. *p<0.05.