Age at blood collection (years) |
58 (54 – 62) |
57 (53 – 61) |
56 (53 – 62) |
57 (53 – 61) |
59 (55 – 63) |
0.02 |
Age at diagnosis (years) |
69 (66 – 73) |
69 (65 – 73) |
69 (66 – 73) |
69 (65 – 73) |
70 (67 – 74) |
0.02 |
Height (cm) |
173 (169 – 177) |
173 (170 – 178) |
174 (170 – 179) |
174 (170 – 178) |
174 (171 – 178) |
0.61 |
Weight (kg) |
75.6 (69.0 – 84.3) |
77.2 (71.0 – 88.0) |
77.7 (70.5 – 86.7) |
80.0 (71.4 – 87.8) |
78.5 (72.1 – 86.2) |
0.23 |
BMI (kg/m2) |
25.8 (23.6 – 28.2) |
26.1 (23.6 – 28.8) |
26.0 (23.9 – 28.3) |
26.1 (24.5 – 28.3) |
25.7 (24.2 – 28.4) |
0.50 |
Cigarettes per day |
20 (13 – 30) |
20 (15 – 25) |
20 (15 – 25) |
20 (15 – 25) |
20 (14 – 25) |
0.44 |
Physically active |
18 (10.8) |
42 (20.7) |
40 (19.4) |
42 (22.5) |
53 (22.4) |
0.06 |
History of diabetes |
7 (4.2) |
5 (2.5) |
3 (1.5) |
2 (1.1) |
5 (2.1) |
0.35 |
Family history of prostate cancer |
11 (6.6) |
6 (3.0) |
3 (1.5) |
15 (8.0) |
17 (7.2) |
0.005 |
Energy intake (kcal/day) |
2,600 (2,104 – 3,261) |
2,643 (2,150 – 3,197) |
2,614 (2,206 – 3,124) |
2,613 (2,125 – 3,130) |
2582 (2,201 – 3,160) |
0.99 |
Dietary vitamin D (IU/day) |
3.5 (2.4 – 4.9) |
4.1 (2.9 – 6.2) |
4.9 (3.3 – 6.5) |
4.9 (3.6 – 6.7) |
5.9 (4.2 – 8.4) |
<0.0001 |
Dietary calcium (mg/day) |
1,326 (974 – 1,825) |
1,329 (966 – 1,725) |
1,306 (1,006 – 1,708) |
1,377 (1.044 – 1.703) |
1,351 (1,003 – 1,710) |
0.85 |
Ethanol intake (g/day) |
9.3 (1.6 – 22.9) |
9.7 (1.9 – 24.5) |
12.1 (2.3 – 27.1) |
10.6 (3.4 – 24) |
11.8 (3.3 – 22.9) |
0.66 |
Supplemental vitamin D use |
1 (0.6) |
9 (4.4) |
18 (8.7) |
18 (9.6) |
32 (13.5) |
0.0005 |
Supplemental calcium use |
15 (9.0) |
17 (8.4) |
24 (11.7) |
21 (11.2) |
39 (16.5) |
0.11 |
Serum cholesterol (mmol/L) |
6.2 (5.4 – 6.8) |
6.2 (5.4 – 6.9) |
6.2 (5.4 – 6.8) |
6.3 (5.5 – 7.1) |
6.1 (5.4 – 6.8) |
0.71 |
Serum alpha-tocopherol (mg/L) |
10.6 (8.6 – 12.9) |
11.1 (9.8 – 13.3) |
11.3 (9.8 – 13.3) |
11.8 (10.2 – 13.9) |
11.8 (10.3 – 13.4) |
<0.0001 |
Serum beta-carotene (μg/L) |
147 (89 – 241) |
169 (116 – 249) |
186 (120 – 259) |
196 (130 – 279) |
213 (139 – 311) |
<0.0001 |
Serum retinol (μg/L) |
575 (497 – 634) |
578 (506 – 666) |
588 (512 – 682) |
603 (515 – 684) |
595 (531 – 686) |
0.21 |
Serum 25(OH)D (nmol/L) |
14.2 (10.5 – 18.4) |
22.7 (20.0 – 29.9) |
30.8 (27.3 – 39.8) |
41.3 (37.4 – 50.3) |
64.1 (53.9 – 74.3) |
- |
Time from baseline to diagnosis (years) |
11.5 (8.1 – 14.5) |
12.7 (8.0 – 15.1) |
12.7 (9.0 – 15.8) |
12.8 (8.2 – 15.0) |
12.8 (9.4 – 15.7) |
0.19 |
Time from diagnosis to death or end of follow-up (years) |
3.9 (1.8 – 8.2) |
4.7 (2.2 – 9.5) |
6.6 (2.8 – 10.2) |
6.6 (2.6 – 10.6) |
6.3 (2.4 – 10.8) |
0.0003 |