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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Cancer Res. 2016 Mar 10;76(8):2206–2218. doi: 10.1158/0008-5472.CAN-15-1046

Figure 2.

Figure 2

Epithelial ovarian tumors expressing homozygous Trp53R172H mutation have early onset and metastasis. A, Representative images of tissue sections stained with H&E, KRT8, or KRT8 and pHH3 on ovaries (top panels) or omentum (bottom panel) from PKP53H/H and PKP53H/+ mice at 4 weeks of age. Regions in frames are shown at higher magnification at the right. Scale bar: 400 μm, 80 μm, and 40 μm. B, Representative images of H&E and KRT8 staining on sections of tumors from intraovarian innoculated PKP53H/H cells. Region in frame is shown at higher magnification at the right. F=follicle; T=tumor; I=intestine; P=pancreas. Scale bar: 750 μm, 200 μm, 100 μm and 50 μm.