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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Cancer Res. 2016 Feb 15;76(8):2115–2124. doi: 10.1158/0008-5472.CAN-15-0749

Figure 2. ETBF triggers colon tumorigenesis in Th17null Min-CD4Stat3-/- mice.

Figure 2

a, colon tumors in parental (Stat3+/+) and CD4Stat3-/- (Stat3-/-) Min mice 8 and 12 weeks after ETBF colonization; Mean+/-SEM. b, representative FFPE sections of rolled colons (left panel) from parental (Stat3+/+; lower panel) and CD4Stat3-/- (Stat3-/-; upper panel) Min mice 3 month after ETBF colonization and micrographic characterization of microadenomas (middle and right panels) in CD4Stat3+/+ (lower panel) and CD4Stat3-/- (upper panel) Min mice 4 weeks after ETBF colonization. c, colonic microadenoma numbers 4, 8 and 12 weeks after ETBF colonization median+/-IQR. p values, non-parametric Mann Whitney U t test.