Figure 8. Hematopoietic miR-33 deficiency enhances autophagy gene expression in the lung and reduces Mtb burden in mice.
Analysis of (a) gene expression and (b) bacterial counts in the lungs of wild type (WT→WT) and Mir33−/− (Mir33−/−→WT) bone marrow chimeric mice infected with H37Rv Mtb for the indicated time post-infection (p.i). *P≤0.05, **P≤0.005 (Student’s t-test (a, b)). Data are from 5 mice (a, b; mean ± s.e.m).