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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Cancer Res. 2016 Feb 26;76(7):1942–1953. doi: 10.1158/0008-5472.CAN-14-0673

Figure 4. Signaling proteins involved in proliferation and programmed cell death are altered with PTP4A3 knockdown.

Figure 4

Two TNBC cell lines (MDA MB231 and HCC1143), and two ER-positive cell lines (MCF-7 and T47D) were transfected with PTP4A3 or control siRNA. After 72hrs cell were harvested and lysed for Western Blot analysis. A) Cleaved caspase 7 is increased after knockdown of PTP4A3 in TNBC cell lines only. B) ERK1/2 phosphorylation and protein levels are reduced after knockdown of PTP4A3. C) Phosphorylation of p38 is reduced after knockdown of PTP4A3.