Table 3.

Predicted mean difference in changes in appetite hormones from baseline by assigned dietary group¹

	Low-fat diet (N=73)	Low-carbohydrate diet (N=75)	Mean difference in changes	P value2
Total Ghrelin (pg/mL)
3 month	18.8 (−21.8, 59.4)	29.8 (−10.0, 69.7)	11.0 (−45.9, 68.0)	0.70
6 month	4.2 (−31.6, 40.0)	10.9 (−24.3, 46.2)	6.7 (−43.6, 57.0)	0.79
12 month	−24.9 (−64.4, 14.6)	−26.9 (−66.2, 12.5)	−2.0 (−57.8, 53.8)	0.94
Total Peptide YY (pg/mL)
3 month	−8.4 (−14.2, −2.5)	−3.8 (−9.5, 1.9)	5.0 (−3.6, 12.7)	0.27
6 month	−20.3 (−24.8, −15.8)	−14.1 (−18.5, −9.7)	6.8 (−0.1, 12.5)	0.055
12 month	−44.2 (−50.4, −38.0)	−34.8 (−41.0, −28.6)	9.4 (0.6, 18.2)	0.036

¹The predicted mean difference in changes in appetite hormones are from the random effects models (including diet and time) and expressed as mean (95% confidence interval).

²P values for the difference between the two groups at each time point