Appendix Table 1.

Predicted mean difference in changes in appetite hormones from baseline by assigned dietary group among whites¹

	Low-fat diet (N=73)	Low-carbohydrate diet (N=75)	Net changes	P value2
Total Ghrelin (pg/mL)
3 month	31.0 (−42.1, 104.1)	31.8 (−41.0, 104.6)	0.8 (−102.5, 104.1)	0.98
6 month	24.4 (−40.4, 89.3)	21.9 (−42.6, 86.4)	−2.5 (−94.2, 89.1)	0.96
12 month	11.4 (−65.5, 88.3)	2.1 (−74.8, 79.0)	−9.3 (−118.2, 99.6)	0.86
Total Peptide YY (pg/mL)
3 month	−15.8 (−24.8, −6.8)	0.7 (−8.3, 9.8)	16.5 (3.8, 29.3)	0.012
6 month	−29.3 (−37.3, −21.3)	−13.0 (−21.0, −5.0)	16.3 (4.9, 27.7)	0.006
12 month	−56.4 (−68.9, −43.9)	−40.5 (−53.1, −27.9)	15.9 (−1.8, 33.6)	0.078

¹The predicted mean difference in changes in appetite hormones are from the random effects models (including diet and time) and expressed as mean (95% confidence interval).

²P values for the difference between the two groups at each time point