Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Gβγ subunits activate PAK1 in response to estrogen. (A, B) Combinations of β1, β2, γ2, γ5 and γ13 subunits were overexpressed. E2-dependent PAK1 activation was assessed in the in vitro kinase assay. Both gray bars in B represent the cells treated with HRG. (C) HA-PAK1 was IP’d from PAK1 WT or Y3F clones overexpressing β1γ2 or β1γ5 subunits and immunoblotted.
