Table 1.
Characteristics of five NCBT genes
| Gene symbol | Locus | Physical position (±5 kb)a | No. of tag SNPs | Encoded protein |
|---|---|---|---|---|
| SLC4A4 | 4q13.3 | chr4:72,048,003-72,442,804 | 42 | electrogenic sodium bicarbonate cotransporter 1,NBCe1 |
| SLC4A5 | 2p13.1 | chr2:74,443,561-74,547,152 | 13 | electrogenic sodium bicarbonate cotransporter 2, NBCe2 |
| SLC4A7 | 3p24.1 | chr3:27,409,212-27,503,245 | 4 | sodium bicarbonate cotransporter 3, NBC3/ NBCn1 |
| SLC4A8 | 12q13.13 | chr12:51,890,612-51,914,547 | 5 | electroneutral sodium bicarbonate exchanger 1,NDCBE |
| SLC4A10 | 2q24.2 | chr2:162,475,845-162,846,786 | 12 | sodium-driven chloride bicarbonate exchanger, NCBE/ NBCn2 |
Abbreviations: SNP, single-nucleotide polymorphism;
a
Genomic locations are based on NCBI Build 37 of the genome.