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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Dev Dyn. 2016 Apr 5;245(6):641–652. doi: 10.1002/dvdy.24403

Figure 10.

Figure 10

Neither cell death nor proliferation is significantly affected in the maxillary domain of pdgfra;pdgfrb mutants. (A–A’, B–B’, C–D) 24 hpf fli1:EGFP zebrafish embryo with corresponding genotypes listed left of panels, stained for active caspase 3 (A and B in red; A’ and B’ in grey), and phospho-histone H3 (pHH3) in (C–D). Anterior is to the left. (B–B’) pdgfra−/−;pdgfrb−/− embryos show increased total cell death at 24 hpf, but not in the maxillary domain crest (arrowheads show cell death above the eye, maxillary domain is outlined in panel A). (E) Bar chart representing either total (grey bars) or maxillary domain (light bars) number of active caspase 3-positive or pHH3-positive fli1:EGFP cells in corresponding genotypes (Students T-test, p=<0.05). scale bar= 100 µm.