Table 1.
Baseline and subjective measures
| Placebo | Diazepam | p value | ||||
|---|---|---|---|---|---|---|
| Baseline | Last day of administration | Baseline | Last day of administration | 1 | 2 | |
| Age | 22.41 (3.94) | – | 23.50 (3.82) | – | 0.41 | |
| IQ (NART) | 113.27 (5.71) | – | 116.84 (5.92) | – | 0.11 | |
| EPQ (N) | 5.12 (3.10) | – | 4.94 (3.12) | – | 0.87 | |
| EPQ (P) | 2.82 (2.51) | – | 3.22 (2.18) | – | 0.62 | |
| EPQ (E) | 16.76 (3.60) | – | 14.94 (3.62) | – | 0.15 | |
| STAI (trait) | 27.41 (5.09) | – | 29.33 (8.23) | – | 0.41 | |
| BDI | 1.35 (1.90) | 1.53 (1.84) | 1.70 (1.90) | 2.76 (2.11) | 0.20 | 0.10 |
| STAI (state) | 25.13 (3.91) | 27.19 (4.43) | 28.47 (7.71) | 30.76 (7.35) | 0.90 | 0.08 |
| VAS | Test day | Test day | ||||
| Alert | – | 69.65 (16.50) | – | 56.28 (23.91) | 0.06 | |
| Disgust | – | 4.41 (7.24) | – | 6.06 (9.38) | 0.57 | |
| Drowsy | – | 27.00 (21.98) | – | 48.61 (17.76) | 0.01 | |
| Anxious | – | 9.94 (11.98) | – | 14.61 (17.77) | 0.37 | |
| Happy | – | 72.29 (13.20) | – | 67.78 (16.14) | 0.37 | |
| Nausea | – | 5.88 (10.20) | – | 13.06 (19.79) | 0.20 | |
| Sadness | – | 5.82 (4.49) | – | 15.44 (19.92) | 0.06 | |
Table shows means and (standard deviations). p values: 1 = between-group difference, 2 = group × time interaction
NART National Adult Reading Test (Nelson 1982), EPQ Eysenck Personality Questionnaire (N neuroticism, P psychoticism, E extroversion; Eysenck et al. 1985), STAI State and Trait Anxiety Inventory (Spielberger et al. 1970), BDI Beck Depression Inventory (Beck et al. 1961), VAS visual analogue scale