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. 2016 Jun 5;125:94–100. doi: 10.1016/j.jpba.2016.03.023

Fig. 2.

Fig. 2

Release of dapivirine in simulated vaginal fluid (SVF) media as compared to the media described in the QC method.

Dissolution conditions: simulated vaginal fluid or 50:50 2-propanol:water, 37 °C, orbital shaker at 60 rpm with 100 ml media, replaced daily (200 ml replacement on Fridays as sampling did not occur on the weekends).