Table 2. Results of the meta-analyses of randomized controlled trials on medical hypnosis*.
| Reference | Datatabases and period covered by literature survey | Results for efficacy [95 % CI]; number of studies/patients (no data on number of studies/patients per outcome variable) |
Results for tolerability and safety [95% CI]; number of studies/patients |
|---|---|---|---|
| Kekecs et al. 2014 (10) |
PubMed. PsycINFO CINAHL. ProQuest from 1980 to February 2014 |
Postoperative anxiety: SMD 0.40 [0.13; 0.66]; 21/1479 Postoperative pain: SMD 0.25 [0.00; 0.50]; no p-value given; 15/1197 Postoperative consumption of painkillers: SMD 0.16 [−0.16; 0.47]. ns; 12/854 Postoperative nausea: SMD 0.38 [−0.06; 0.81). ns at α -level of p<0.01; 16/647 |
No data |
| Madden et al. 2012 (11) |
Cochrane Pregnancy and Childbirth Group’s Trials Register/Central. PubMed. Embase up to January 2012 | Drug treatment for pain: RR 0.63 [0.39; 1.01]. ns; 6/1032 Spontaneous vaginal delivery: RR1.35 [0.93; 1.96]. ns; 4/472 Satisfaction with pain reduction: RR1.06 [0.94; 1.20]. ns; 1/264 |
Resuscitation of newborns: RR: 0.67 [0.11;3.96]. ns; 1/520 Intensive care of newborns: RR: 0.58 [0.12; 2.89]. ns; 2/347 Intensive care of mothers: RR: 1.47 [0.25; 8.68]. ns; 1/305 Inpatient re-admission of newborns: RR: 1.39 [0.64; 3.02]. ns; 1/267 |
| Schaefert et al. 2014 (12) |
Allied und Complementary Medicine Database Central Register of Controlled Trials. CINAHL. PubMed. PsycINFO. Scopus up to June 2013 (restricted to studies published in journals) |
At end of treatment: Adequate reduction of symptoms: RR 1.69 [1.14; 2.51]; NNT 5 [3; 10]; 5/280 Reduction of global gastrointestinal symptoms: SMD 0.32; [0.08; 0.56]; 6/361 Follow-up (6 months): Adequate reduction of symptoms: RR 2.17 [1.22; 3.87]; NNT 3 [2; 10]; 1/90 Reduction of global gastrointestinal symptoms: SMD 0.57 [–0.26; 1.40]. ns; 2/171 |
Data from five studies: one patient reported dizziness. but continued treatment; one patient discontinued treatment due to a panic attack during hypnosis |
| Schnur et al. 2008 (13) |
PsycINFO and PubMed from beginning to February 2008 (restricted to English-language studies published in journals) | Emotional stress: SMD 0.88 [0.57; 1.19]; 26/2342 |
No data |
| Tefikow et al. 2013 (14) |
Central. PubMed. Web of Science. ProQuest up to September 2011 | Emotional stress: SMD 0.53 [0.37; 0.69) Pain: SMD 0.44; [0.26; 0.61] Drug consumption: SMD 0.38 [0.20; 0.56] Physiological parameters: SMD 0.10 [0.02; 0.18]; ns Duration of convalescence: SMD 0.25 [0.04; 0.46] Operation time: SMD 0.25 [0.12; 0.38]; ns |
No data |
*The meta-analyses are listed in alphabetical order CI. confidence interval; ns. not significant; p. probability; RR. relative risk; SMD. standardized mean difference; NNT. number needed to treat