Table 2. Sensitivity Analysis.
Assuming that a treatment has a constant effect on the time to HD (HR 0.8, top row), the increase in time with HD is shown with decreasing effect sizes on survival with HD as the HR increases from 0.80 to 0.95.
| Quintiles of Time to HD | ||||||
|---|---|---|---|---|---|---|
| Hazard Ratio for Survival with HD |
1 | 2 | 3 | 4 | 5 | |
|
Increase in Time to HD on Treatment mean(SD) |
0.7 (0.1) |
1.4 (0.3) |
2.7 (0.5) |
4.5 (0.6) |
8.1 (2.3) |
|
|
Increase in Time with HD on treatment mean(SD) |
0.80 | 5.2 (2.9) |
5.3 (2.9) |
5.3 (3.1) |
5.2 (2.9) |
5.3 (3.0) |
|
Increase in Time with HD on treatment mean(SD) |
0.85 | 3.7 (2.1) |
3.7 (2.1) |
3.7 (2.2) |
3.7 (2.1) |
3.7 (2.1) |
|
Increase in Time with HD on treatment mean(SD) |
0.90 | 2.3 (1.3) |
2.3 (1.3) |
2.4 (1.4) |
2.3 (1.3) |
2.3 (1.3) |
|
Increase in Time with HD on treatment mean(SD) |
0.95 | 1.1 (0.6) |
1.1 (0.6) |
1.1 (0.7) |
1.1 (0.6) |
1.1 (0.6) |