Table 2.

Minor Allele Frequencies of SNPs and Hazard Ratios for Incident AF using an Additive Genetic Model

SNP	Genetic Locus	MAF (%)	HR (95% CI)	p value	Adjusted HR (95% CI)†	Adjusted p value
rs2200733	4q25	14.2	1.20 (1.05–1.37)	0.007	1.27 (1.11–1.45)	0.001
rs2106261	16q22	15.8	1.09 (0.95–1.25)	0.235	1.08 (0.94–1.25)	0.274
rs6666258	1q21	28.7	1.13 (1.01–1.26)	0.038	1.11 (0.99–1.25)	0.063
rs3903239	1q24	42.7	0.93 (0.84–1.04)	0.190	0.95 (0.85–1.06)	0.340
rs3807989	7q31	40.0	0.92 (0.84–1.01)	0.088	0.90 (0.82–0.99)	0.032
rs10821415	9q22	42.2	1.02 (0.92–1.13)	0.742	1.00 (0.90–1.11)	0.928
rs10824026	10q22	16.2	0.85 (0.73–0.98)	0.026	0.82 (0.71–0.95)	0.01
rs1152591	14q23	46.3	1.07 (0.96–1.18)	0.237	1.08 (0.98–1.20)	0.127
rs7164883	15q24	16.9	1.10 (0.95–1.26)	0.192	1.09 (0.95–1.26)	0.223

^†Adjusted for baseline age, gender, body mass index, diabetes, and hypertension. SNP = single nucleotide polymorphism, MAF = minor allele frequency, HR = hazard ratio, CI = confidence interval.