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. 2016 May 20;6:26202. doi: 10.1038/srep26202

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Copyright © 2016, Macmillan Publishers Limited

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(A) Mean cross sectional area (CSA) of myofibers in the tibialis anterior in wild-type and Pus1^−/− mice. Data are expressed as the percentage of wild-type to account for differences in size between male and female mice. (B) The percentage of extracellular matrix area in the tibialis anterior in wild-type and Pus1^−/− mice. Data are expressed as the percentage of extracellular matrix area to the total myofiber area. (C) The percentage of centralized nuclei in the tibialis anterior in wild-type and Pus1^−/− mice. Data are expressed as the percentage of total myofibers containing centralized nuclei. Muscles from 13 wild-type and 9 Pus1^−/− were examined. Data were analyzed with t-Tests and significance was set at p < 0.05. An asterisk (*) indicates the results for Pus1^−/− mice are significantly different from wild-type mice at p < 0.05.