Table 1.
Baseline characteristics of women in the GLOW USA cohort and in the low -and high-risk fracture groups.
| GLOW USA cohort (n=27,957) | Low riska (n=3013) | High riskb (n=3699) | |
|---|---|---|---|
| Age (years) | 69 ± 9.1 | 60 ± 2.5 | 75 ± 7.0 |
| BMI (kg/m2) | 28 ± 6.4 | 29 ± 6.8 | 27 ± 5.9 |
| Vitality score | 61 ± 20.4 | 66 ± 18.7 | 59 ± 21.0 |
| Physical function score | 72 ± 27.7 | 85 ± 20.0 | 65 ± 28.2 |
| Number of co-morbidities | |||
| 0 | 4408 (19.3) | 1011 (34.2) | 435 (12.6) |
| ≥1 | 18,400 (80.7) | 1943 (65.8) | 3025 (87.4) |
| General health | |||
| Excellent, very good, or good | 23,275 (84.4) | 2805 (93.5) | 2995 (81.7) |
| Fair or poor | 4313 (15.6) | 195 (6.5) | 669 (18.3) |
| Prescription drug coverage | |||
| Yes | 25,591 (92.4) | 2841 (94.5) | 3411 (92.6) |
| No | 2094 (7.6) | 167 (5.5) | 274 (7.4) |
| Concern about osteoporosis | |||
| Very/somewhat | 23,604 (85.1) | 2603 (86.4) | 3228 (87.7) |
| Not at all | 4129 (14.9) | 408 (13.6) | 452 (12.3) |
| Perceived fracture risk | |||
| Same or lower than others | 21,702 (79.6) | 2597 (87.1) | 2474 (68.0) |
| Higher than others | 5558 (20.4) | 386 (12.9) | 1166 (32.0) |
| Education | |||
| High school or less | 9211 (33.5) | 441 (14.7) | 1363 (37.6) |
| More than high school | 18,246 (66.5) | 2564 (85.3) | 2265 (62.4) |
| Race | |||
| White | 23,925 (86.6) | 2696 (90.0) | 3372 (92.1) |
| Non-white | 3706 (13.4) | 299 (10.0) | 290 (7.9) |
Data are mean ± SD for continuous variables and number (%) for discrete variables.
BMI, body mass index; GLOW, Global Longitudinal study of Osteoporosis in Women; SD, standard deviation.
a
Low risk: age <65 years, no FRAX risk factors, cnot on estrogen.
b
High risk: age ≥65 years and prior fracture or ≥2 FRAX risk factors, cnot on estrogen.
c
FRAX risk factors: parental hip fracture, current smoker, prior fracture, ≥3 alcoholic drinks/day, rheumatoid arthritis, current corticosteroid use, BMI <20 kg/m2, secondary osteoporosis.