Skip to main content
. 2016 May 20;6:26449. doi: 10.1038/srep26449

Figure 3. The effect of strain (10–70%) and frequency of compressive loading (1 Hz, 0.1 Hz and 0 Hz) on the relative level of gene expression.

Figure 3

The HSR genes: (a) HSP70, (b) HSF1, (c) HSP27, and (d) HSP90, and UPR genes: (e) GRP78, (f) GRP94, (g) ATF4, and (h) CHOP were only upregulated slightly, after compressive loading for one hour. Asterisks indicate statistically significant differences (p < 0.05). In each case, the mean ± 2SE fold change of gene expression was normalized to the control without loading. n = 10 (control); n = 4 (1 Hz); n = 6 (0.1 Hz) and n = 8 (0 Hz).