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. 2016 May 20;6:26449. doi: 10.1038/srep26449

Figure 4. The effect of loading duration and type of compressive loading (dynamic and static) on the relative level of gene expression.

Figure 4

The HSR genes: (a) HSP70, (b) HSF1, (c) HSP27, and (d) HSP90, and UPR genes: (e) GRP78, (f) GRP94, (g) ATF4, and (h) CHOP demonstrated different expression patterns for the different loading type. Asterisks indicate statistically significant differences (p < 0.05). In each case, the mean ± 2SE fold change of gene expression was normalized to the control without loading. n = 3 for each sample.