Table 2. Metabolomic analysis. Metabolites that largely differentiate control (C), sedentary diabetics (D) and exercise-trained diabetics (DX) from the red portion of the gastrocnemius are presented.

Identity	Empirical Formula	Mass (m/z)	tR(min)	P[1]P	p(corr)[1]P	S-plot VIP score	Fold change	Effect	ID level
Inosine monophosphate	C10H13N4O8P	347.0477	0.7	−0.190376	−0.593433	12.6789	5.1	↑C vs D	2
ADP Ribose	C15H23N5O14P2	558.0647	0.65	−0.102561	−0.501781	7.15977	2.8	↑C vs D	2
Adenylosuccinic acid	C14H18N5O11P	462.0664	1.07	−0.114934	−0.612991	7.96882	7.8	↑C vs D	2
Pantothenic acid	C9H17NO5	218.1026	1.23	−0.103502	−0.65815	7.64157	2.0	↑C vs D	2
Arachidonic acid	C20H32O2	303.2326	6.68	0.111519	0.501134	7.64936	1.6	↑D vs C	2
				−0.165695	−0.716968		2.4	↑D vs DX
Palmitic acid	C16H32O2	255.2323	7.42	0.152801	0.800222	10.7176	2.6	↑D vs C	1
				−0.131925	−0.634719		2.2	↑D vs DX
Octadecenoic acid	C18H34O2	281.248	7.63	0.215689	0.844199	14.9743	3.6	↑D vs C	2
			−0.165018	−0.603556		2.2	↑D vs DX
Docosahexaenoic acid	C22H32O2	327.2325	6.5	0.221078	0.773611	16.1763	2.7	↑D vs C	2
Linoleic acid	C18H32O2	279.2322	6.82	0.279119	0.858839	19.7256	3.3	↑D vs C	2
				−0.216401	−0.648384		2.0	↑D vs DX
Flavine adenine dinucleotide (FAD)	C27H33P2N9O15	784.1504	1.33	0.133381	0.677607	6.84121	6.7	↑DX vs D	2
Pantetheine 4′-phosphate	C11H23N2O7PS	357.0886	1.23	0.125091	0.597866	1.22198	3.0	↑DX vs D	2
Unknown	–	347.0394	0.97	−0.140527	−0.529978	10.0537	3.2	↑ C vs D	2
				0.175433	0.646263		3.7	↑ DX vs D
Unknown	–	558.0647	0.65	−0.102561	−0.501781	7.15977	2.8	↑ C vs D	2
Unknown	–	329.2481	6.88	−0.16972	−0.826997	11.8857	3.4	↑ D vs C	2
				−0.16972	−0.826997		3.3	↑ D vs DX
Unknown	–	347.0392	0.7	0.257514	0.590923	0.377651	1.9	↑ DX vs D	2
Unknown	–	695.0872	1.23	0.154213	0.604018	1.221986	2.2	↑ DX vs D	2